Quick answer: Trulicity cost without insurance is about $987 a month: Lilly’s list price is $987.19 for a box of four weekly pens, the same for every dose.[1] The $25 Trulicity Savings Card does not apply if you have no insurance.[2] Lower-cost routes include LillyDirect and, for people with low incomes, the Lilly Cares Foundation.[3][5]
Prices and program terms checked October 2026. They change often; confirm with the manufacturer or your plan.
Trulicity is the brand name for dulaglutide, a once-weekly GLP-1 injection for type 2 diabetes. It also lowers the risk of heart attack and stroke in adults with type 2 diabetes and heart disease or risk factors.[4] For other drugs in this class, see our GLP-1 and weight-loss drugs hub.
Trulicity list price by dose
| Dose | Pack | List price (WAC) |
|---|---|---|
| 0.75 mg | 4 pens | $987.19 |
| 1.5 mg | 4 pens | $987.19 |
| 3 mg | 4 pens | $987.19 |
| 4.5 mg | 4 pens | $987.19 |
Source: Lilly’s state pricing disclosure, based on prices accessed January 2025.[1] WAC (wholesale acquisition cost) is the price Lilly charges wholesalers before discounts. Pharmacies set their own cash prices, which can be higher.
One box lasts four weeks, since each pen holds one weekly dose.[4] At list price, a year (13 boxes) comes to about $12,830.
Is there a generic Trulicity?
No. Dulaglutide is a biologic, and no generic or biosimilar version is sold in the U.S. CMS could only pick Trulicity for Medicare price negotiation because it has no generic or biosimilar competition.[6] So the brand is the only option, and its price is set by Lilly.
Why list price matters
If you have no insurance, the pharmacy’s cash price usually starts from the list price. The list price also matters for people with insurance who pay a deductible or a percentage (coinsurance), because their share is based on it. That is why two people with the same drug can pay very different amounts.
The cash price can also vary from one pharmacy to the next, even on the same street. Pharmacies set their own retail prices, so it is worth calling a few, including mail-order pharmacies, and asking for the price of one box of four Trulicity pens at your dose.
Why the savings card won’t help without insurance
Lilly’s Trulicity Savings Card can bring the cost down to as little as $25 for a 1-, 2- or 3-month fill. But you must have commercial drug insurance that covers Trulicity.[2]
Card terms, as of October 2026:
- Savings of up to $150 per 1-month fill, $300 per 2-month fill or $450 per 3-month fill.[2]
- Up to $1,950 per calendar year and 13 fills.[2]
- Expires December 31, 2026.[2]
- Not for people with Medicare, Medicaid or other government coverage.[2]
If your insurance does not cover Trulicity, or you have none, the card does not apply.
If you are between jobs or plans: a gap in coverage is a common reason people suddenly face the full price. Before your coverage ends, ask your prescriber whether a 90-day supply makes sense, and fill it while the card still applies. If you are buying a new plan, check that plan’s formulary for Trulicity first, since the card only helps when the plan covers the drug.[2]
LillyDirect self-pay
As part of its November 2025 agreement with the federal government, Lilly said it would add Trulicity to LillyDirect, its direct-to-patient pharmacy service, at 50-60% off list price.[3] At list price, that would mean roughly $395 to $494 a month. That range is our math, not a published Lilly price; we could not confirm the current figure, so check LillyDirect or call Lilly before you fill.
Self-pay purchases usually do not count toward an insurance deductible.
Lilly Cares: free Trulicity for some people
The Lilly Cares Foundation is Lilly’s patient assistance program. It lists Trulicity among medicines available to people who have no insurance or Medicare Part D and a household income at or below 300% of the federal poverty level.[5]
To apply:
- Download the application from the Lilly Cares website.
- Have your prescriber complete their section.
- Include proof of income.
- Reapply when your enrollment ends; approvals are time-limited.[5]
Cheaper options to ask your prescriber about
Trulicity is one of several GLP-1 drugs for type 2 diabetes. If cost is the barrier, ask your prescriber whether another option makes sense:
| Drug | Cash price per month | Source |
|---|---|---|
| Trulicity (list) | $987.19 | Lilly[1] |
| Ozempic pen, self-pay | $349 (0.25-1 mg); $499 (2 mg) | NovoCare[7] |
| Ozempic pill, self-pay | $149-$299 by dose | NovoCare[7] |
Generic liraglutide, the same medicine as Victoza, is another lower-cost GLP-1 for diabetes; prices vary by pharmacy. For a clinical comparison, see dulaglutide vs semaglutide.
Trulicity is not approved for weight loss. If weight management is your main goal, the drugs and prices are different; our Foundayo cost guide covers a lower-cost GLP-1 pill approved for weight loss.
Will Trulicity get cheaper?
For people on Medicare, possibly. In January 2026, CMS selected Trulicity for the third round of Medicare drug price negotiation. CMS must publish any agreed price by November 30, 2026, and it would take effect January 1, 2028.[6] A negotiated Medicare price does not directly change the cash price for uninsured people. See Trulicity cost with Medicare for details.
How to lower your cost today
- Ask for a cash quote at several pharmacies; prices differ.
- Check LillyDirect for the current self-pay price.[3]
- Apply to Lilly Cares if your income qualifies.[5]
- Check marketplace or employer coverage. Diabetes drugs are commonly covered, and once you have a plan that covers Trulicity, the $25 card may apply.[2]
- Ask about alternatives with published self-pay prices, such as Ozempic.[7]
